interferon-α相关论文
Functional Restoration of HBsAg-specific B cells Associates HBsAg Seroconversion in Patients with Ch
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Interferon-α suppresses invasion and enhances cisplatin-mediated apoptosis and autophagy in human os
Interferon-(IFN-α) is generated in response to viral infections and used clinically in the therapy of a variety of vira......
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目的:探讨干扰素α对白血病Raji细胞生长的抑制作用及其作用机制.方法:以不同浓度的干扰素α作用于体外培养的Raji细胞,应用MTT法......
AIM: To evaluate the efficacy of combination chemotherapy with interferon-α(IFNα) and 5-fluorouracil(5-FU) in patients......
We report a case of severe thrombocytopenia following pegylated interferon-α 2a (Peg-IFN-α 2a) treatment of hepatitis ......
Predictors for Efficacy of Combination Therapy with a Nucleos(t)ide Analogue and Interferon for Chro
This study aims to explore the efficacy of interferon-α (IFN-α) combined with either entecavir (ETV) or adefovir (ADV)......
目的 评价干扰素-α(IFN-α)对慢性骨髓增殖性肿瘤(MPN)患者的临床疗效.方法 回顾性分析110例进展期MPN病例,其中包括76例JAK2V617......
Effect of Hepatitis C Virus Core Protein on Interferon-Induced Antiviral Genes Expression and Its Me
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,Minimal residual disease-directed immunotherapy for high-risk myelodysplastic syndrome after alloge
The efficacy of minimal residual disease (MRD)-directed immunotherapy,including interferon-α (IFN-α) treatment and che......
,Interferon-α salvage treatment is effective for patients with acute leukemia/myelodysplastic syndro
The efficacy of salvage interferon-α (IFN-α) treatment was investigated in patients with unsatisfactory response to mi......
Clinical study on the treatment of liver fibrosis due to hepatitis B by IFN-α1 and traditional medic
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Antitumor Effect of Interferon-α on U937 Human Acute Leukemia Cells in vitro and Its Molecular Mecha
In order to investigate the antitumor effect and molecular mechanism of interferon-α(IFN-α) on human acute myeloid leu......
Association of T regulatory cells with natural course and response to treatment with interferon-α in
Background Regulatory T cell populations,particularly cD4+CD25* T regulatory cells,have been implicated in the persisten......
Background Peg-lnterferon-α treatment is expensive and associated with considerable adverse effects,selection of patien......
目的研究干扰素α对慢性丙型病毒性肝炎(CHC)患者甲状腺功能的影响。方法随机收集97例CHC患者,观察使用干扰素后出现甲状腺功能异......
Effect of Hepatitis C Virus Core Protein on Interferon-Induced Antiviral Genes Expression and Its Me
Emerging data indicated that HCV subverts the antiviral activity of interferon (IF); however,whether HCV core protein co......
目的探讨重组干扰素-α(IFN-α)对肿瘤抑制作用的靶分子及可能作用机制。方法选用HepG2肝癌细胞系,分别应用1000 U/ml、2000 U/ml......
IFN-α以抗病毒及免疫调节双莺作用用于慢性乙型肝炎的治疗,对治疗反应的早期预测有利于治疗的持续.随着人类基因组学和蛋白质组学......
目的 评价阿德福韦治疗经IFN-α治疗12周无应答的慢性乙型肝炎患者的疗效和安全性.方法 36例经IFN-α治疗12周,复查HBeAg仍阳性且H......
系统性红斑狼疮(sLE)是一种常见的自身免疫性疾病,多数患者血清中干扰素-α(IFN-α)水平升高,并且在淋巴细胞和组织中出现大量IFN......
Antitumor Effect of Interferon-α on U937 Human Acute Leukemia Cells in vitro and Its Molecular Mecha
In order to investigate the antitumor effect and molecular mechanism of interferon-α(IFN-α) on human acute myeloid leu......
目的 探讨小剂量阿司匹林协同干扰素-α(IFN-α)诱导肝癌BEL-7402细胞凋亡的作用及机制.方法 体外培养的人肝癌BEL-7402细胞经IFN-......
Association of T regulatory cells with natural course and response to treatment with interferon-α in
Background Regulatory T cell populations,particularly cD4+CD25* T regulatory cells,have been implicated in the persisten......
目的了解干扰素α(IFN-α)对骨肉瘤U2OS细胞化疗敏感性的影响。方法细胞分为对照组、IFN-α组、顺铂组和IFN-α+顺铂组,处理72 h,......
目的：探讨IFN-α对慢性乙型病毒肝炎抗肝纤维化的治疗作用。方法：血清TGFβ1检测采用酶联免疫吸附试验法，HA、LN和PCⅢ测定均采用放射......
目的：探讨α-干扰素（IFN-α）联合5-FU对肝癌细胞HepG2．2．15生物学特性的影响及其作用机制。方法：采用MTT法观察5-FU和IFN-α对HepG2．2．15细......
采用PCR法从绍兴鸭的肝组织基因组DNA中扩增出α-干扰素基因,插入pUC18载体,进行序列测定及分析;将成熟α-干扰素基因亚克隆到表达......
根据GenBank中鸭IFN-α基因（GenBank登录号：JF894229）序列设计并合成引物,并以鸭β-actin基因（GenBank登录号：GU564232）为内参,采用SYBR ......
为研究鸡α-干扰素对罗曼雏鸡免疫功能的影响，将60羽健康1日龄罗曼雏鸡随机分为2组，即对照组、试验组。试验组鸡于1日龄胸肌注射鸡-......
目的：评估慢性乙型肝炎及其并发症的经济负担和α-干扰素（IFN-α）治疗的临床效果与经济效益。方法：根据慢性乙型肝炎、代偿性肝硬化、......
目的探讨干扰素治疗慢性乙型肝炎出现HBsAg血清转换后再转为阳性对病情的影响。方法5例慢性乙型肝炎患者在使用干扰素治疗发生HBsA......
目的探讨干扰素α(IFNα)对肝纤维化的治疗作用.方法雄性SD大鼠40只,采用复合因素造成肝硬化模型,随机取12只作为A组(模型组),余大......
客观：调查干扰素的禁止的效果 -- α(Raji 房间(B-NHL ) 和它的机制的增长上的 IFN- α) andcurcumin。方法：Raji 房间的词法变化与 ......
目的:探讨MP方案(马法兰和强的松)联合α-干扰素治疗多发性骨髓瘤的临床疗效、感染发生情况和对患者生存期的影响.方法:用随机对照......
目的检测原发性舍格伦综合征（pSS）患者唇腺中干扰素（IFN）-α的表达水平,探讨其在pSS发病机制产生的作用。方法对41例pSS患者和32例非pS......
目的：观察干扰素-α对CCl4诱导的SD大鼠肝纤维化治疗作用,并探讨其机制。方法：SD雄性大鼠39只,随机分为正常组（n=10）,每只大鼠给予花生......
本研究通过PCR从晋南黄牛(Yellow cattle)基因组DNA中克隆了IFN—α(BolFN—α)基因，PCR产物酶切后直接与载体PQE30连接，构建重组质......
为探讨针刺与α-干扰素联用对慢型乙型肝炎的临床治疗价值,将58例慢型乙型肝炎患者随机分为两组,一组为针刺与α-干扰素联合治疗组......
目的探讨HBeAg阳性慢性乙型肝炎（CHB）患者干扰素-α（IFN-α）疗效的影响因素。方法收集105例HBeAg阳性CHB患者,检测IFN-α治疗前及治疗1......
目的:探讨血清干扰素α(IFN-α)与乙型肝炎病毒相关性肾炎(HBV-GN)发生发展的相关性. 方法: [5"K]通过ELISA方法检测实验组与对照......
目的:探讨慢性乙型肝炎肝纤维化及早期肝硬化的中西医结合疗法.方法:采用α-干扰素加中药软坚散结汤联合治疗经病理确诊的慢性乙型......
观察干扰素α-2b联合利巴韦林治疗不同途径感染的慢性丙型肝炎的疗效。对154例慢性丙型肝炎患者根据感染途径不同分为三组,进行干......
报道家蚕细胞基因工程人α－干扰素注射液具有明显抗ＨＳＶ－２的作用。在Ｖｅｒｏ细胞上，其有一定的细胞毒性，但随浓度降低而毒性减少；明显地抑制ＨＳＶ－２所致细胞......
从健康奶牛的血液中分离白细胞，用刺激物诱导白细胞产生干扰素，采用RT—PCR扩增干扰素-α基因，构建原核表达载体pQE30-IFNα，用IPTG诱......
目的；总结报告１例多中心性巨大淋巴结增生症的诊断与治疗，并对其发病机制，临床表现及治疗进行了讨论。方法：采用化疗及干扰素治疗，结果：用......
